| Product Type: | Rabbit polyclonal IgG, primary antibodies |
|---|---|
| Species reactivity: | Human, Rat, Mouse |
| Applications: | WB |
| Clonality: | Polyclonal |
| Form: | Liquid |
| Storage condition: | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage buffer: | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Concentration: | 1ug/ul |
| Purification: | Immunogen affinity purified. |
| Molecular weight: | 76 kDa |
| Isotype: | IgG |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 210-290 |
| Positive control: | B-cell lymphoma,Liver,Testis, |
| Recommended Dilutions:
WB |
1:500-1:2000 |
| Uniprot #: | SwissProt: P33121 Human |
| Alternative names: | ACS 1 ACS1 ACSL 1 ACSL1 ACSL1_HUMAN Acyl CoA synthetase 1 Acyl CoA synthetase long chain family member 1 Acyl-CoA synthetase 1 FACL 1 FACL 2 FACL1 FACL2 Fatty acid Coenzyme A ligase long chain 1 Fatty acid Coenzyme A ligase long chain 2 LACS 1 LACS 2 LACS LACS1 LACS2 Lignoceroyl CoA synthase Long chain acyl CoA synthetase 1 Long chain acyl CoA synthetase 2 Long chain fatty acid CoA ligase 1 Long chain fatty acid CoA ligase 2 Long chain fatty acid coenzyme A ligase 1 Long-chain acyl-CoA synthetase 1 Long-chain acyl-CoA synthetase 2 Long-chain fatty acid-CoA ligase 2 Long-chain-fatty-acid--CoA ligase 1 Palmitoyl CoA ligase 1 Palmitoyl CoA ligase 2 Palmitoyl-CoA ligase 1 Palmitoyl-CoA ligase 2 Paltimoyl CoA ligase 1 |
|
Fig1: Bicyclol with or without berberine enhances the lipolysis and β-oxidation through p62-Nrf2-CES2/PPARα axis. Male C57BL/6J mice were freely fed with WD or WD plus bicyclol and/or berberine for 16 weeks (A,C), or induced with WD/CCl4 for 4 weeks and then treated with drugs for 8 weeks (B,D). The protein levels of PPARα, CES2, Nrf2, p62, CD36, FABP1, ATGL, HSL, ACSL1, and ACSL5 were detected with Western blot and quantified using a Gel-Pro analyzer.(PMID: 35250593) |