ET1704-55

Product Type:	Recombinant Rabbit monoclonal IgG, primary antibodies
Species reactivity:	Human
Applications:	WB, IP, IHC-P, FC
Clonality:	Monoclonal
Clone number:	JA03-38

Form:

Liquid

Storage condition:

Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.

Storage buffer:

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Concentration:

1ug/ul

Purification:

Protein A affinity purified.

Molecular weight:

48 kDa

Isotype:

IgG

Immunogen:

Synthetic peptide within Human DR5 aa 391-440 / 440.

Positive control:

HL-60, human tonsil tissue, human liver tissue, human colon cancer tissue, human placenta tissue, SW480.

Subcellular location:

Membrane.

Recommended Dilutions:
  WB
  IHC-P
  FC

1:500-1:1,000
1:50-1:200
1:50-1:100

Uniprot #:

SwissProt: O14763 Human

Alternative names:

Fas like protein Apoptosis inducing protein TRICK2A/2B Apoptosis inducing receptor TRAIL R2 CD262 CD262 antigen Cytotoxic TRAIL receptor 2 Death domain containing receptor for TRAIL/Apo 2L Death receptor 5 DR5 KILLER KILLER/DR5 OTTHUMP00000123492 OTTHUMP00000123493 p53 regulated DNA damage inducible cell death receptor(killer) TNF related apoptosis inducing ligand receptor 2 TNF-related apoptosis-inducing ligand receptor 2 TNFRSF10B TR10B_HUMAN TRAIL R2 TRAIL receptor 2 TRAIL-R2 TRAILR2 TRICK2 TRICK2A TRICK2B TRICKB Tumor necrosis factor receptor like protein ZTNFR9 Tumor necrosis factor receptor superfamily member 10B Tumor necrosis factor receptor superfamily, member 10b ZTNFR9

	Fig1: Western blot analysis of DR5 on HL-60 cell using anti-DR5 antibody at 1/1,000 dilution.
	Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DR5 antibody. Counter stained with hematoxylin.
	Fig3: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-DR5 antibody. Counter stained with hematoxylin.
	Fig4: Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-DR5 antibody. Counter stained with hematoxylin.

	Fig5: Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-DR5 antibody. Counter stained with hematoxylin.
	Fig6: Flow cytometric analysis of SW480 cells with DR5 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).