Human Osteoactivin/GPNMB, C-His Tag (ECD) Protein
cat.: HA210623
| Product name: |
Human Osteoactivin/GPNMB, C-His Tag (ECD) |
| Catalog No.: |
HA210623 |
| Bio-Activity: |
Testing in progress. |
| Purity: |
>95% as determined by SDS-PAGE. |
| Endotoxin: |
Less than 1.0 EU per μg by the LAL method. |
| Formulation: |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
| Background: |
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. |
| Source: |
HEK293 |
| Storage: |
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Reconstitution: |
Reconstitute at 250 μg/ml in sterile water. |