Human Clusterin, C-His, Flag Tag Protein
cat.: HA210955
Product name: |
Human Clusterin, C-His, Flag Tag |
Catalog No.: |
HA210955 |
Bio-Activity: |
Testing in progress. |
Purity: |
>95% as determined by SDS-PAGE. |
Endotoxin: |
Less than 1.0 EU per μg by the LAL method. |
Formulation: |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
Background: |
Clusterin (apolipoprotein J) is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging. |
Source: |
HEK293 |
Storage: |
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Reconstitution: |
Reconstitute at 250 μg/ml in sterile water. |