Human Fas/TNFRSF6/CD95, C-His Tag (ECD) Protein
cat.: HA211064
| Product name: | Human Fas/TNFRSF6/CD95, C-His Tag (ECD) |
|---|---|
| Catalog No.: | HA211064 |
| Bio-Activity: | Testing in progress. |
| Purity: | >95% as determined by SDS-PAGE. |
| Endotoxin: | Less than 1.0 EU per μg by the LAL method. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
| Background: | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis. |
| Source: | HEK293 |
| Storage: | Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Reconstitution: | Reconstitute at 250 μg/ml in sterile water. |
Images
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Fig1: Protein on SDS-PAGE under reducing (R) condition. |
Note: All products are “FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE”.