Human SOST/Sclerostin, Tag Free Protein
cat.: HA211397
| Product name: | Human SOST/Sclerostin, Tag Free |
|---|---|
| Catalog No.: | HA211397 |
| Bio-Activity: | Testing in progress. |
| Purity: | >95% as determined by SDS-PAGE. |
| Endotoxin: | Less than 1.0 EU per μg by the LAL method. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
| Background: | Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced primarily by the osteocyte but is also expressed in other tissues, and has anti-anabolic effects on bone formation. |
| Source: | HEK293 |
| Storage: | Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Reconstitution: | Reconstitute at 250 μg/ml in sterile water. |
Images
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Fig1: Protein on SDS-PAGE under reducing (R) condition. |
Note: All products are “FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE”.