Human GFR alpha-like, Tag Free Protein
cat.: HA211457
| Product name: |
Human GFR alpha-like, Tag Free |
| Catalog No.: |
HA211457 |
| Bio-Activity: |
Testing in progress. |
| Purity: |
>95% as determined by SDS-PAGE. |
| Endotoxin: |
Less than 1.0 EU per μg by the LAL method. |
| Formulation: |
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol. |
| Background: |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. |
| Source: |
HEK293 |
| Storage: |
Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃ It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Reconstitution: |
Reconstitute at 250 μg/ml in sterile water. |