Product Type: | Alpaca monoclonal VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation), primary antibodies |
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Species reactivity: | Human |
Applications: | ELISA, FC |
Clonality: | Monoclonal |
Form: | Liquid |
Storage condition: | Store at –20 ℃, (Avoid freeze / thaw cycles), Stable for 12 months at -20℃ |
Storage buffer: | Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol |
Concentration: | 1ug/ul |
Purification: | Immunogen affinity purified. |
Isotype: | VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation) |
Immunogen: | Recombinant human CD38 |
Subcellular location: | Membrane |
Recommended Dilutions:
ELISA FC |
1:4,000-1:10,000 1:200-1:1,000 |
Uniprot #: | SwissProt: P28907 Human |
Alternative names: | Acute lymphoblastic leukemia cells antigen CD38 ADP ribosyl cyclase 1 ADP ribosyl cyclase ADP ribosyl cyclase/cyclic ADP-ribose hydrolase ADP-ribosyl cyclase 1 ADPRC 1 ADPRC1 cADPr hydrolase 1 CD 38 CD38 CD38 antigen (p45) CD38 antigen CD38 molecule Cd38-rs1 CD38_HUMAN CD38H Cyclic ADP ribose hydrolase Cyclic ADP ribose hydrolase 1 Cyclic ADP-ribose hydrolase 1 EC 3.2.2.5 Ecto nicotinamide adenine dinucleotide glycohydrolase I-19 I19 (mouse) Lymphocyte differentiation antigen CD38 NAD(+) nucleosidase NIM-R5 antigen NIMR5 antigen (mouse) OTTHUMP00000158633 OTTHUMP00000217743 p45 T10 |
Fig1:
Advantages of using an Alpaca Recombinant Secondary 1. Smaller size Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies. 2. Easier to use Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use. 3. Easier production When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies. 4. More consistent Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift. 5. Higher Affinity Nanobodies benefit from consistently high binding affinity values. |