Product Type: | Alpaca monoclonal VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation), primary antibodies |
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Species reactivity: | Human |
Applications: | ELISA, FC |
Clonality: | Monoclonal |
Form: | Liquid |
Storage condition: | Store at –20 ℃, (Avoid freeze / thaw cycles), Stable for 12 months at -20℃ |
Storage buffer: | Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol |
Concentration: | 1ug/ul |
Purification: | Immunogen affinity purified. |
Isotype: | VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation) |
Immunogen: | Recombinant human FOLR1 |
Subcellular location: | Cell membrane |
Recommended Dilutions:
ELISA FC |
1:4,000-1:10,000 1:200-1:1,000 |
Uniprot #: | SwissProt: P15328 Human |
Alternative names: | adult Adult folate binding protein Adult folate-binding protein FBP Folate Binding Protein Folate Receptor 1 Adult Folate receptor 1 Folate Receptor 1 Precursor Folate receptor adult Folate receptor alpha Folate receptor FOLR FOLR1 FOLR1_HUMAN FR alpha FR-alpha FRalpha KB cells FBP MOV18 Ovarian cancer associated antigen Ovarian tumor associated antigen Ovarian tumor associated antigen MOv18 Ovarian tumor-associated antigen MOv18 |
Fig1:
Advantages of using an Alpaca Recombinant Secondary 1. Smaller size Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies. 2. Easier to use Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use. 3. Easier production When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies. 4. More consistent Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift. 5. Higher Affinity Nanobodies benefit from consistently high binding affinity values. |