Product Type: | Alpaca monoclonal VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation), primary antibodies |
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Species reactivity: | Human |
Applications: | ELISA, FC |
Clonality: | Monoclonal |
Form: | Liquid |
Storage condition: | Store at –20 ℃, (Avoid freeze / thaw cycles), Stable for 12 months at -20℃ |
Storage buffer: | Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol |
Concentration: | 1ug/ul |
Purification: | Immunogen affinity purified. |
Isotype: | VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation) |
Immunogen: | Recombinant human CD70 |
Subcellular location: | Membrane |
Recommended Dilutions:
ELISA FC |
1:4,000-1:10,000 1:200-1:1,000 |
Uniprot #: | SwissProt: P32970 Human |
Alternative names: | CD 27L CD 70 CD27 L CD27 LG CD27 ligand CD27-L CD27L CD27LG CD70 CD70 antigen CD70 molecule CD70_HUMAN Ki 24 antigen Ki24 antigen Surface antigen CD70 TNFSF 7 TNFSF7 Tumor necrosis factor (ligand) superfamily member 7 Tumor necrosis factor ligand superfamily member 7 |
Fig1:
Advantages of using an Alpaca Recombinant Secondary 1. Smaller size Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies. 2. Easier to use Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use. 3. Easier production When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies. 4. More consistent Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift. 5. Higher Affinity Nanobodies benefit from consistently high binding affinity values. |