CD33, AlpHcAbs® Human Alpaca Monoclonal Antibody
cat.: HA710344
Product Type: Alpaca monoclonal VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation), primary antibodies
Species reactivity: Human
Applications: ELISA, FC
Clonality: Monoclonal
Form: Liquid
Storage condition: Store at –20 ℃, (Avoid freeze / thaw cycles), Stable for 12 months at -20℃
Storage buffer: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol
Concentration: 1ug/ul
Purification: Immunogen affinity purified.
Isotype: VHH domain of alpaca IgG2b/2c fused to Human IgG1 Fc(mutation)
Immunogen: Recombinant human CD33
Subcellular location: Cell membrane, Peroxisome
Recommended Dilutions:
  ELISA
  FC

1:4,000-1:10,000
1:200-1:1,000
Uniprot #: SwissProt: P20138 Human
Alternative names: CD 33 CD33 CD33 antigen (gp67) CD33 antigen CD33 molecule CD33_HUMAN FLJ00391 gp67 My9 Myeloid cell surface antigen CD33 Myeloid cell surface antigen CD33 precursor Myeloid differentiation antigen CD33 p67 Sialic acid binding Ig like lectin 3 Sialic acid binding immunoglobulin like lectin 3 Sialic acid-binding Ig-like lectin 3 SIGLEC 3 Siglec-3 SIGLEC3
Images
HA710344_1.jpg Fig1: Advantages of using an Alpaca Recombinant Secondary
1. Smaller size
Nanobodies are 1/10 the size of a traditional antibody (~15 kDa unconjugated). This means that the nanobody can penetrate tissue faster and deeper than other antibodies.
2. Easier to use
Due to their simple structure, nanobodies also have the advantage of increased stability and ease of use.
3. Easier production
When compared to a more traditional antibody, nanobodies are easier to develop and produce in the lab than monoclonal or polyclonal antibodies.
4. More consistent
Since nanobodies are recombinantly produced from clonal DNA, you are guaranteed the same product every time. Comparatively, polyclonal antibodies are produced in live animals and have a very low lot-to-lot consistency while monoclonal antibodies can suffer from drift.
5. Higher Affinity
Nanobodies benefit from consistently high binding affinity values.
Note: All products are “FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE”.